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Human antibodies produced in lab for first time

 25th July, 2017
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In a first, researchers, led by Facundo Batista from the Francis Crick Institute in the UK, produced specific human antibodies in the laboratory by treating patient-derived B cells with tiny nanoparticles coated with both CpG oligonucleotides and an antigen. This technique could usher the rapid development of new vaccines to treat a wide range of infectious diseases.

Antibodies are produced by the body's B cells to fight off infections by bacteria, viruses, and other invasive pathogens. When an individual B cell recognises a specific pathogen-derived "antigen" molecule, it can proliferate and develop into plasma cells that secrete large amounts of antibody capable of binding to the antigen and fending off the infection.


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